WebPeyronie’s disease happens when scar tissue, or plaque, forms on the shaft of the penis and causes a noticeable hard lump or band of tissue. This is known as “waisting” or “bottlenecking.” WebAug 30, 2024 · If men find hard lumps under the skin of their penis or on side of the shaft, usually the first thing that comes to mind is the fear of cancer. But significantly more often than penile cancer, however, lumps on the penis may indicate peyronie’s disease. Penile cancer: Mostly a form of skin cancer
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